{"id":869,"date":"2026-10-12T17:01:16","date_gmt":"2026-10-12T17:01:16","guid":{"rendered":"https:\/\/avo6.com\/?page_id=869"},"modified":"2026-10-12T17:01:17","modified_gmt":"2026-10-12T17:01:17","slug":"coagulation","status":"publish","type":"page","link":"https:\/\/avo6.com\/?page_id=869","title":{"rendered":"Coagulation"},"content":{"rendered":"\n<p>L\u2019INR standardise le temps de Quick pour la surveillance des antivitamines K. Son calcul d\u00e9pend de l\u2019ISI du r\u00e9actif et du MNPT \u00e9tabli par le laboratoire.<\/p>\n\n<div class=\"a6t-group a6t-has-tabs\" data-a6t-group=\"coagulation\"><nav class=\"a6t-tabs\" aria-label=\"Outils de cette page\"><ul><li><a href=\"#inr\" data-a6t-tab=\"inr\">INR<\/a><\/li><li><a href=\"#ratio-temoin\" data-a6t-tab=\"ratio-temoin\">Rapport patient\/t\u00e9moin<\/a><\/li><\/ul><\/nav>\t<section class=\"a6t-tool\" id=\"inr\" data-a6t-panel aria-labelledby=\"a6t-inr-title\">\n\t\t<h2 id=\"a6t-inr-title\" class=\"a6t-title\">INR (rapport normalis\u00e9 international)<\/h2>\n\t\t<p class=\"a6t-lead\">INR \u00e0 partir du temps de Quick du patient, du MNPT et de l\u2019ISI du r\u00e9actif.<\/p>\n\n\t\t<form class=\"calc a6t-form\" data-a6t-tool=\"inr\" novalidate autocomplete=\"off\" aria-label=\"Calculateur : INR\">\n\t\t\t\t\t\t<fieldset class=\"a6t-fieldset\" disabled>\n\t\t\t\t<legend class=\"screen-reader-text\">Donn\u00e9es \u00e0 saisir<\/legend>\n\t\t\t\t<div class=\"field a6t-field\"><label for=\"a6t-inr-pt\">Temps de Quick du patient (s)<\/label><input id=\"a6t-inr-pt\" name=\"pt\" type=\"text\" inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" value=\"\" aria-describedby=\"a6t-inr-pt-err\" aria-required=\"true\"><span class=\"error\" id=\"a6t-inr-pt-err\" data-a6t-err-for=\"pt\" aria-live=\"polite\"><\/span><\/div><div class=\"field a6t-field\"><label for=\"a6t-inr-mnpt\">MNPT du laboratoire (s)<\/label><input id=\"a6t-inr-mnpt\" name=\"mnpt\" type=\"text\" inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" value=\"\" aria-describedby=\"a6t-inr-mnpt-hint a6t-inr-mnpt-err\" aria-required=\"true\"><span class=\"hint\" id=\"a6t-inr-mnpt-hint\">Moyenne g\u00e9om\u00e9trique des temps de plasmas normaux.<\/span><span class=\"error\" id=\"a6t-inr-mnpt-err\" data-a6t-err-for=\"mnpt\" aria-live=\"polite\"><\/span><\/div><div class=\"field a6t-field\"><label for=\"a6t-inr-isi\">ISI du r\u00e9actif<\/label><input id=\"a6t-inr-isi\" name=\"isi\" type=\"text\" inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" value=\"\" aria-describedby=\"a6t-inr-isi-hint a6t-inr-isi-err\" aria-required=\"true\"><span class=\"hint\" id=\"a6t-inr-isi-hint\">Indiqu\u00e9 pour le lot et l\u2019analyseur (notice).<\/span><span class=\"error\" id=\"a6t-inr-isi-err\" data-a6t-err-for=\"isi\" aria-live=\"polite\"><\/span><\/div>\t\t\t\t<div class=\"a6t-actions\">\n\t\t\t\t\t<button type=\"submit\" class=\"btn btn-primary\">Calculer<\/button>\n\t\t\t\t\t<button type=\"reset\" class=\"btn btn-ghost\">R\u00e9initialiser<\/button>\n\t\t\t\t\t<button type=\"button\" class=\"a6t-linkbtn\" data-a6t-example>Essayer l\u2019exemple<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/fieldset>\n\t\t\t<p class=\"error a6t-formerror\" data-a6t-err-for=\"_\" role=\"alert\"><\/p>\n\n\t\t\t<div class=\"calc-result a6t-result\" role=\"status\" aria-live=\"polite\" tabindex=\"-1\" hidden>\n\t\t\t\t<div class=\"a6t-main\"><\/div>\n\t\t\t\t<ul class=\"a6t-lines\"><\/ul>\n\t\t\t\t<div class=\"a6t-chart\"><\/div>\n\t\t\t\t<div class=\"a6t-table\"><\/div>\n\t\t\t\t<p class=\"a6t-formula\"><\/p>\n\t\t\t\t<ul class=\"a6t-notes\"><\/ul>\n\t\t\t\t<p class=\"hint\">R\u00e9sultat indicatif, \u00e0 interpr\u00e9ter par un professionnel de sant\u00e9.<\/p>\n\t\t\t\t<div class=\"a6t-result-actions\">\n\t\t\t\t\t<button type=\"button\" class=\"btn btn-ghost\" data-a6t-copy>Copier le r\u00e9sultat<\/button>\n\t\t\t\t\t<span class=\"a6t-copied\" aria-live=\"polite\"><\/span>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\n\t\t\t<noscript><p class=\"notice\">Ce calculateur fonctionne dans votre navigateur et n\u00e9cessite JavaScript. La formule et un exemple sont d\u00e9taill\u00e9s ci-dessous.<\/p><\/noscript>\n\t\t\t<script type=\"application\/json\" class=\"a6t-example-data\">{\"pt\":\"30\",\"mnpt\":\"12\",\"isi\":\"1,1\"}<\/script>\n\t\t<\/form>\n\n\t\t<div class=\"a6t-doc\">\n\t\t\t<h3>Formule<\/h3>\n\t\t\t<div class=\"a6t-formula-box\"><p>INR = (TP patient \/ MNPT)<sup>ISI<\/sup><\/p><\/div>\n\n\t\t\t<h3>Unit\u00e9s<\/h3>\n\t\t\t<p>Secondes ; INR sans unit\u00e9.<\/p>\n\n\t\t\t<h3>Exemple<\/h3>\n\t\t\t<p>TP 30 s, MNPT 12 s, ISI 1,1 : (30 \/ 12)^1,1 = 2,7.<\/p>\n\n\t\t\t<h3>Limites<\/h3>\n\t\t\t<ul>\n\t\t\t\t\t\t\t\t\t<li>L\u2019INR est valid\u00e9 pour la surveillance des antivitamines K ; il n\u2019est pas adapt\u00e9 aux autres anticoagulants ni \u00e0 l\u2019\u00e9valuation d\u2019une h\u00e9patopathie.<\/li>\n\t\t\t\t\t\t\t\t\t<li>L\u2019ISI doit correspondre au lot de r\u00e9actif et \u00e0 l\u2019analyseur ; le MNPT est \u00e9tabli localement.<\/li>\n\t\t\t\t\t\t\t<\/ul>\n\n\t\t\t<h3>R\u00e9f\u00e9rences<\/h3>\n\t\t\t<ol class=\"a6t-refs\">\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.who.int\/publications\/m\/item\/annex-6-trs-no-979\" rel=\"noopener\" target=\"_blank\">OMS. Guidelines for thromboplastins and plasma used to control oral anticoagulant therapy with vitamin K antagonists. S\u00e9rie de rapports techniques n\u00b0 979, annexe 6 ; 2013.<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/zentrallabor.uk-essen.de\/wp-content\/uploads\/2023\/09\/Besselaar-JThrombHaemost-2-1490-2004.pdf\" rel=\"noopener\" target=\"_blank\">van den Besselaar AMHP, Poller L, Tripodi A. Definition of the International Normalized Ratio (INR) and its consequences for the calibration procedure of thromboplastin preparations: a rebuttal. J Thromb Haemost. 2004;2:1490-1491.<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<\/ol>\n\t\t\t<p class=\"a6t-verified\">Formule v\u00e9rifi\u00e9e par rapport aux r\u00e9f\u00e9rences ci-dessus le 12 octobre 2026.<\/p>\n\t\t<\/div>\n\t<\/section>\n\t\t<section class=\"a6t-tool\" id=\"ratio-temoin\" data-a6t-panel aria-labelledby=\"a6t-ratio-temoin-title\">\n\t\t<h2 id=\"a6t-ratio-temoin-title\" class=\"a6t-title\">Rapport patient\/t\u00e9moin (TP, TCA)<\/h2>\n\t\t<p class=\"a6t-lead\">Rapport entre le temps de coagulation du patient et celui du t\u00e9moin (TCA, temps de Quick).<\/p>\n\n\t\t<form class=\"calc a6t-form\" data-a6t-tool=\"ratio-temoin\" novalidate autocomplete=\"off\" aria-label=\"Calculateur : Rapport patient\/t\u00e9moin\">\n\t\t\t\t\t\t<fieldset class=\"a6t-fieldset\" disabled>\n\t\t\t\t<legend class=\"screen-reader-text\">Donn\u00e9es \u00e0 saisir<\/legend>\n\t\t\t\t<div class=\"field a6t-field\"><label for=\"a6t-ratio-temoin-patient\">Temps du patient (s)<\/label><input id=\"a6t-ratio-temoin-patient\" name=\"patient\" type=\"text\" inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" value=\"\" aria-describedby=\"a6t-ratio-temoin-patient-err\" aria-required=\"true\"><span class=\"error\" id=\"a6t-ratio-temoin-patient-err\" data-a6t-err-for=\"patient\" aria-live=\"polite\"><\/span><\/div><div class=\"field a6t-field\"><label for=\"a6t-ratio-temoin-control\">Temps du t\u00e9moin (s)<\/label><input id=\"a6t-ratio-temoin-control\" name=\"control\" type=\"text\" inputmode=\"decimal\" autocomplete=\"off\" spellcheck=\"false\" value=\"\" aria-describedby=\"a6t-ratio-temoin-control-err\" aria-required=\"true\"><span class=\"error\" id=\"a6t-ratio-temoin-control-err\" data-a6t-err-for=\"control\" aria-live=\"polite\"><\/span><\/div>\t\t\t\t<div class=\"a6t-actions\">\n\t\t\t\t\t<button type=\"submit\" class=\"btn btn-primary\">Calculer<\/button>\n\t\t\t\t\t<button type=\"reset\" class=\"btn btn-ghost\">R\u00e9initialiser<\/button>\n\t\t\t\t\t<button type=\"button\" class=\"a6t-linkbtn\" data-a6t-example>Essayer l\u2019exemple<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/fieldset>\n\t\t\t<p class=\"error a6t-formerror\" data-a6t-err-for=\"_\" role=\"alert\"><\/p>\n\n\t\t\t<div class=\"calc-result a6t-result\" role=\"status\" aria-live=\"polite\" tabindex=\"-1\" hidden>\n\t\t\t\t<div class=\"a6t-main\"><\/div>\n\t\t\t\t<ul class=\"a6t-lines\"><\/ul>\n\t\t\t\t<div class=\"a6t-chart\"><\/div>\n\t\t\t\t<div class=\"a6t-table\"><\/div>\n\t\t\t\t<p class=\"a6t-formula\"><\/p>\n\t\t\t\t<ul class=\"a6t-notes\"><\/ul>\n\t\t\t\t<p class=\"hint\">R\u00e9sultat indicatif, \u00e0 interpr\u00e9ter par un professionnel de sant\u00e9.<\/p>\n\t\t\t\t<div class=\"a6t-result-actions\">\n\t\t\t\t\t<button type=\"button\" class=\"btn btn-ghost\" data-a6t-copy>Copier le r\u00e9sultat<\/button>\n\t\t\t\t\t<span class=\"a6t-copied\" aria-live=\"polite\"><\/span>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\n\t\t\t<noscript><p class=\"notice\">Ce calculateur fonctionne dans votre navigateur et n\u00e9cessite JavaScript. La formule et un exemple sont d\u00e9taill\u00e9s ci-dessous.<\/p><\/noscript>\n\t\t\t<script type=\"application\/json\" class=\"a6t-example-data\">{\"patient\":\"45\",\"control\":\"30\"}<\/script>\n\t\t<\/form>\n\n\t\t<div class=\"a6t-doc\">\n\t\t\t<h3>Formule<\/h3>\n\t\t\t<div class=\"a6t-formula-box\"><p>Rapport = temps patient \/ temps t\u00e9moin<\/p><\/div>\n\n\t\t\t<h3>Unit\u00e9s<\/h3>\n\t\t\t<p>Secondes ; rapport sans unit\u00e9.<\/p>\n\n\t\t\t<h3>Exemple<\/h3>\n\t\t\t<p>TCA patient 45 s, t\u00e9moin 30 s : rapport = 1,50.<\/p>\n\n\t\t\t<h3>Limites<\/h3>\n\t\t\t<ul>\n\t\t\t\t\t\t\t\t\t<li>Le seuil d\u2019allongement d\u00e9pend du r\u00e9actif et du laboratoire.<\/li>\n\t\t\t\t\t\t\t\t\t<li>Le taux de prothrombine (TP en %) se lit sur la droite d\u2019\u00e9talonnage du laboratoire : il ne se calcule pas par ce rapport.<\/li>\n\t\t\t\t\t\t\t<\/ul>\n\n\t\t\t<h3>R\u00e9f\u00e9rences<\/h3>\n\t\t\t<ol class=\"a6t-refs\">\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.who.int\/publications\/m\/item\/annex-6-trs-no-979\" rel=\"noopener\" target=\"_blank\">OMS. Guidelines for thromboplastins and plasma used to control oral anticoagulant therapy with vitamin K antagonists. S\u00e9rie de rapports techniques n\u00b0 979, annexe 6 ; 2013.<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<\/ol>\n\t\t\t<p class=\"a6t-verified\">Formule v\u00e9rifi\u00e9e par rapport aux r\u00e9f\u00e9rences ci-dessus le 12 octobre 2026.<\/p>\n\t\t<\/div>\n\t<\/section>\n\t<aside class=\"box box-warning a6t-disclaimer\" role=\"note\"><strong>Avertissement :<\/strong> ces outils sont p\u00e9dagogiques. Les calculs sont effectu\u00e9s dans votre navigateur ; aucune valeur n\u2019est enregistr\u00e9e ni transmise. Ils ne posent pas de diagnostic et ne remplacent pas l\u2019avis d\u2019un m\u00e9decin, d\u2019un biologiste ou d\u2019un pharmacien.<\/aside><nav class=\"a6t-related\" aria-labelledby=\"a6t-rel-coagulation\"><h2 id=\"a6t-rel-coagulation\">Outils associ\u00e9s<\/h2><ul><li><a href=\"https:\/\/avo6.com\/?page_id=859\">Calculs d\u2019h\u00e9matologie : formule, indices et r\u00e9ticulocytes<\/a><\/li><li><a href=\"https:\/\/avo6.com\/?page_id=867\">Biostatistiques et contr\u00f4le qualit\u00e9<\/a><\/li><li><a href=\"https:\/\/avo6.com\/?page_id=857\">Tous les outils de biologie m\u00e9dicale<\/a><\/li><\/ul><\/nav><\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>L\u2019INR standardise le temps de Quick pour la surveillance des antivitamines K. Son calcul d\u00e9pend de l\u2019ISI du r\u00e9actif et du MNPT \u00e9tabli par\u2026<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"class_list":["post-869","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.3 - aioseo.com -->\n\t<meta name=\"description\" content=\"L\u2019INR standardise le temps de Quick pour la surveillance des antivitamines K. 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